The Welsh midfielder sustained an injury while leading the team to a 1-1 draw against Huddersfield last Saturday.
The 29-year-old has experienced a succession of knee ailments; during his tenure with the club, he has already had three setbacks.
And after trying to play through agony, the celebrity disclosed in a message posted on social media that he’s ultimately opted to have surgery to repair the problem.
The highs and lows of football, he wrote. This week’s operation comes after this time last week’s captaincy of the club against Premier League opponents and its league game on Saturday.
“I’ve tried so hard to play through pain, with the issues I’ve had over the last couple of seasons and avoid surgery so I can be back available for the club as soon as possible, whenever they needed me, it was always my priority.
“However the time has come to have the surgery which will fix all the issues l’ve been having and get me back to playing my best football again!
“Thank you to everyone for your messages of support they mean a lot! Let’s get it.”
Speaking after Town’s win against Hull City on Tuesday night, boss Kieran McKenna said: “Lee Evans unfortunately has an MCL (medial collateral ligament) injury, so he’s going to have a surgery tomorrow.
“It’s very disappointing for him and for the football club because he’s a great player and person.
“Having spoken to him, I think hopefully now he can resolve the couple of issues he’s had with a surgical repair.
“That will leave him out for quite a while but, all being well, should hopefully give him a knee in really, really good condition which will give him a chance to have a good run at his career again, because he’s been really unlucky with it.